Preoperative cardiovascular risk assessment in cancer patients AN INTEGRATIVE REVIEW OF THE LITERATURE
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Abstract
Cancer patients can be challenging in the preoperative evaluation, either due to the limited time between the evaluation and the surgical procedure, or due to various associated risk factors such as previous exposure to chemotherapy, advanced age, drug interactions, and degree of frailty. This study consists of an integrative review of the literature, which seeks to answer how to assess the cardiovascular surgical risk of cancer patients in relation to elective surgeries, with the objective of identifying the risks that this specific population may present, and how to manage these patients in order to avoid further complications in the perioperative period. The integrative review is a type of literature review whose methodology is broader, allowing the inclusion of varied studies, whether experimental or non-experimental. The steps for the elaboration of this review article are based on the work of Souza et al. (2010), which consists of the elaboration of an integrative review, divided into six stages. Of the total of 99 articles selected for full-text reading, 23 were selected and the main levels of evidence found were for descriptive and analytical studies, with a quantitative approach (12; 52%) and literature reviews (11.48%). A scarcity of controlled and randomized experimental articles in this patient profile has been demonstrated. This study shows that there are still knowledge gaps in cardio-oncology in the context of surgical patients, and efforts to study this patient profile are necessary.
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References
Sahai SK; Zalpour A; Rozner MA. Preoperative Evaluation of the Oncology Patient. Heart Failure Clin 7 (2011) 413-426. https://doi.org/10.1016/j.hfc.2011.04.003
Kimmick GG; Lenihan DJ; Sawyer DB; Mayer EL. Hershman DL. Cardio – Oncology. The Clinical Overlap of Cancer and Heart Disease. Springer,2016. In: Goodman S; Cornell RF; Rosner GF ; O’Connor DS. Chapter 6 Preoperative and Pre-transplant Cardiac Evaluation in Cancer Patiets. p. 125-140.
SOUZA, MT; SILVA, MD; CARVALHO R. Revisão Integrativa: o que é e como fazer. einstein. 2010; 8(1 Pt 1):102-6.
Herrmann J. Cardio-oncology practice manual: a companion to Braunwald’s heart disease. Elsevier, 2023. In: Trachtenberg HB; Reardon MJ.Chapter 6 Surgical Risks. p.59-68.
Cohn SL. Preoperative Cardiac Evaluation of Lung Resection Candidates. Thoracic Surgery Clinics.18. 2008. 45-59. doi:10.1016/j.thorsurg.2007.11.006
Vogelsang RP; Soby JH; Tolstrup MB; Burcharth J; Ekelof S; Gogenur I. Assoaciations between malignancy and cardiovascular complications following emergency laparotomy – A retrospective cohort study. Surgical Oncology.2021.38. 1-5. doi:10.1016/j.suronc.2021.101591
Pedrazzini C; Cerullo G; De Marco G;Marreli D, Roviello F et al. Impact of age related comorbidity on results of colorectal cancer surgery. World Journal of Gastroenterology.2009. 15(45): 5706-5711. doi:10.3748/wjg.15.5706
Tran TB; Worhunsky DJ; Spain DA; Dua MM; Visser BC et al. The significance of underlying cardiac comorbidity on major adverse cardiac events after major liver resection. Hepato-Pancreato-Biliary HPB. 2016.18. 742–747.doi: 10.1016/j.hpb.2016.06.012
Moraes CMT; Correa LM; Procópio RJ; Carmo GAL; Navarro TP. Ferramentas e escores para avaliação de risco perioperatório gera e cardiovascular: Uma Revisão Narrativa. Revista do Colégio Brasileiro de Cirurgiões. 2021.49.1-13. doi: 10.1590/0100-6991e-20223124
Ferguson MK; Celauro AD; Vingneswaran WT. Validation of Modified Scoring System for Cardiovascular Risk Associated with major lung resection. European Journal of Cardio-thoracic Surgery.2012. 41. 598–601. doi:10.1093/ejcts/ezr081.
Gomez-Henao PA; Carreño-Dueñas JÁ. Cardiovascular pre-anesthesia evaluation in oncology surgery. Revista Colombiana de Anestesiologia. 2016. 44(1):17–22
Miralpeix E; Mancebo G; Gayete S; Corcoy M; Solé-Sedeño JM. Role and Impact of multimodal prehabilitation for gynecologic oncology patients in na Enhanced Recovery After Surgery (ERAS) program. Int J Gynecol Cancer. 29.2019. 1235-1243. doi:10.1136/ijgc-2019-000597
Halvorsen S; Mehili J; Cassese S; Hall TS; Abdelhamid M; Barbato E. 2022 ESC Guideline on cardiovascular assessment and management of patients undergoing non-cardiac surgery. European Heart Journal.2022.43. 3826-3924. doi: 10.1093/eurheartj/ehac270.
Shapiro R; Barsuk D; Segev L; Shimon-Paluch S; Papa MZ et al. Pre-operative cardiac workuo after anthracycline-based neoadjuvant chemotherapy. Is it really necessary?. The Annals of the Royal College of Surgeons of England. 2011. 93: 127–129. doi 10.1308/003588411X12851639107836.
Mercantini P; Di Somma S; Magrini L; Kazemi A. Petrucciani N et al. Preoperative Brain Natriuretic Peptide ( BNP) is a better predictor of adverse cardiac events compared to preoperative scoring system who underwent abdominal surgery?. World Journal of Surgery. 2011. 36:24–30. doi10.1007/s00268-011-1354-6
Lagoeiro Jorge AJ; Mesquita ET; Martins WS. Lesão Miocardica após Cirurgia Não Cardíaca. Arquivos Brasileiros de Cardiologia. 2021. 117(3):544-553. DOI: https://doi.org/10.36660/abc.20200317
Noordzij PG; Van Geffen O; Dijkstra IM; Boerma D; Meinders AJ; Van Dongen EPA et al. High-sensitive cardiac troponin T measurements in prediction of non-cardiac complications after major abdominal surgery. British Journal of Anesthesia; 114 (6);2015; 909-18. doi: 10.1093/bja/aev027
Brown LB; Streiff MB; Haut ER. Venous Thromboembolism prevention and Treatment in Cancer Surgery. Advances in Surgery. 2020.2-14. https://doi.org/10.1016/j.yasu.2020.04.002
Yap KPL; McCready DR. Deep Vein Thrombosis and Malignancy: A Surgical Oncologist’s Perspective. Asian Journal of Surgery. 2004. VOL 27.N 3.249-254.
Bellini G; Teng A; Kotecha N; Rose K et al. The identification of risk factors for venous thromboembolism in gastrointestinal oncologic surgery. Journal of Surgical Research. October 2016 (205) 279-285. http://dx.doi.org/10.1016/j.jss.2016.06.089
Ruff SM; Weber KT; Khader A; Conte C; Kadison A et al. Venous Thromboembolism in patients with cancer undergoing surgical exploration. Journal of Thrombosis and Thrombolysis. 2018. https://doi.org/10.1007/s11239-018-1774-3
Emoto S; Nozawa H; Kawai K; Tanaka HK; Shuno Y et al. Venous thromboembolism in colorectal surgery: incidence, risk factors and prophylaxis. Asian Journal of Surgery. 2019. 42, 863 e 873. https://doi.org/10.1016/j.asjsur.2018.12.013
Xiuying Lu; Weirong Zeng MS; et al. Application of the Caprini risk assessment model for deep thromboses among patient undergoing laparoscopic surgery for colorectal cance. Medicine. 2021.p 100:4. http://dx.doi.org/10.1097/MD.0000000000024479
D’Austous J; Liedermean Z; Doukelis D. Venous Thromboemlism Prophylaxis in High-risk orthopedic and cancer surgery. Posgraduate Medicine.2021. https://doi.org/10.1080/00325481.2021.1891751
Kanitra J; Holtrop J; Jawad Ali; Berri R. Extended duration chemoprophylaxis for venous thromboemlism following abdominopelvic oncologic surgery. Journal of Thrombosis and Thrombolysis. 2019. https://doi.org/10.1007/s11239-019-02002-9
Fabiani I; Colombo A; Bacchiani G; Cipolla CM, Cardinale DM. Incidence, management, prevention and Outcome of Post-operative atrial Fibrillation in Thoracic Surgical Oncology. J.Clin Med. 2020.p 2-17. doi:10.3390/jcm9010037
Seesing MFJ; Scheijmans JCG; Borggreve AS; Van Hillegersber R; Ruurda JP. The predictive value of new-onset atrial fibrillation on postoperative morbidity after esophagectomy. Diaseases of the Esophagus. 2018. 31.1–9 doi: 10.1093/dote/doy028