Infective endocarditis due to a cardiac pacemaker infection: a case report

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Lucas Bonacossa Sant'Anna
https://orcid.org/0000-0002-6987-3905
Igor Martins Moreira
Helena Carvalho Boechat
Camile Torres Andriani
Victoria Depes Scaramussa
Mariana Bonacossa Sant’Anna
https://orcid.org/0000-0003-2080-2767
Eliane Almeida do Valle
Eduardo Xavier Hias Pozzobon
Fernando Mendes Sant'Anna
https://orcid.org/0000-0003-3998-8813
Aloysio Guimarães da Fonseca

Resumo

Introduction: Infective endocarditis (IE) related to cardiac implantable electronic devices (CIED) is a potentially fatal complication that may compromise the generator, leads, or cardiac valves. Most cases occur in multimorbid patients and are frequently caused by Staphylococcus aureus or S. epidermidis.


Case report: An elderly patient with a dual-chamber pacemaker implanted four years earlier was ad­mitted with sepsis, fever, and acute kidney injury. On examination, exposure of the generator unit with purulent discharge was noted. Echocardiography showed vegetations on the ventricular lead and the right atrial wall, and blood cultures were positive for S. aureus. Computed tomography revealed mul­tiple cavitary nodules compatible with septic emboli. Device extraction was performed, followed by pathogen-directed antibiotic therapy for four weeks, with favorable progression and hospital discharge without sequelae.


Conclusion: CIED-related IE requires rapid diagnosis and aggressive management. Microbiological confirmation, early detection of complications, and device removal combined with appropriate antibi­otics were decisive for the favorable outcome.


Keywords: infective endocarditis; artificial pacemaker; cardiac implantable electronic device

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Bonacossa Sant’Anna, L., Martins Moreira, I., Carvalho Boechat, H., Torres Andriani, C., Depes Scaramussa, V., Bonacossa Sant’Anna, M., Almeida do Valle, E., Xavier Hias Pozzobon, E., Mendes Sant’Anna, F., & Guimarães da Fonseca, A. (2026). Infective endocarditis due to a cardiac pacemaker infection: : a case report. OnScience, 4(1), e0073. https://doi.org/10.33634/2764-0736.2026.0073
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